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Conversely, Th2 cells produce IL-4, IL-5 and IL-13 which drive alternative macrophage activation, increase arginase activity, and promote parasite survival ( Quiescent naïve T cells, recently matured in the thymus following clonal selection, primarily rely on OxPhos to meet energy demands, occasionally supplementing with glycolysis during intermediate stages after T cell receptor (TCR) rearrangements ( Table 1 ) (103)

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What Can Be Done: If you suspect your dog is experiencing cognitive dysfunction, talk to your vet about cognitive health supplements or medications designed to support brain function